APPLIED RESEARCH

Economic burden of schizophrenia on healthcare systems of the Russian Federation and the Republic of Belarus: direct medical costs, productivity losses and the impact of maintenance therapy programmes

Authors

  • Anna A. Makarevich-Konstantinova Petrozavodsk State University, 185910, Russia, Republic of Karelia, Petrozavodsk, Lenina ave. 33
  • Aleksandriia I. Makarevich-Konstantinova Belarusian State Medical University, 220083, Republic of Belarus, Minsk, Dzerzhinsky ave. 83

How to cite

GOST Makarevich-Konstantinova A. A., Makarevich-Konstantinova A. I. Economic burden of schizophrenia on healthcare systems of the Russian Federation and the Republic of Belarus: direct medical costs, productivity losses and the impact of maintenance therapy programmes // Academic Research Journal. 2026. Vol. 4. No. 1. P. 202-214. DOI: 10.25726/e8217-3774-2177-p
APA Makarevich-Konstantinova, A. A. & Makarevich-Konstantinova, A. I. (2026). Economic burden of schizophrenia on healthcare systems of the Russian Federation and the Republic of Belarus: direct medical costs, productivity losses and the impact of maintenance therapy programmes. Academic Research Journal, 4(1), 202-214. https://doi.org/10.25726/e8217-3774-2177-p

Abstract

The work is devoted to a comprehensive analysis of the economic burden of schizophrenia on the healthcare systems of the Russian Federation and the Republic of Belarus. The study assesses direct medical costs associated with the treatment and rehabilitation of patients and also calculates productivity losses due to disability and reduced work capacity. During the research, epidemiological data on schizophrenia in the Russian Federation and the Republic of Belarus were analysed, and current expenditures on inpatient and outpatient care, drug therapy, and rehabilitation measures were estimated. Particular attention is paid to the impact of maintenance therapy programmes on reducing the frequency and duration of hospitalisations and on increasing patients’ employment rates. The methodology includes statistical and comparative analysis of data from national ministries of health, modelling of economic indicators using a productivity-loss formula, and a review of scientific publications and clinical trial results. The results show that the economic burden of schizophrenia consists of significant direct costs and even more substantial productivity losses. Implementation of maintenance therapy programmes can reduce the overall burden by 10-15% through fewer hospitalisations and improved patient work capacity. Based on the findings, recommendations are formulated to optimise financing of mental healthcare, develop outpatient support, and implement work adaptation programmes. The research results can be used by healthcare authorities in the Russian Federation and the Republic of Belarus for budget planning and improvement of psychiatric care systems.

Keywords

schizophrenia economic burden direct medical costs productivity losses healthcare systems of the Russian Federation healthcare systems of the Republic of Belarus maintenance therapy programmes hospitalisation work adaptation psychosocial rehabilitation disability epidemiological data mental healthcare financing outpatient care

References

Gustavsson A., Svensson M., Jacobi F. Cost of disorders of the brain in Europe 2010 // European Neuropsychopharmacology. 2011. Vol. 21. № 10. pp. 718-779.

Insel T., Schoenbaum M., Wang P. Components of the economic burden of serious mental illness in the US // US Neurology. 2009. Vol. 5. № 1. pp. 10-11.

Khmaruk I.N., Mrykhina V.V., Soldatkin V.A. et al. Mothers of schizophrenic patients: medical and psychological aspects of the problem // Medical Herald of the South of Russia. 2019. Vol. 10. № 3. pp. 6-17.

Kooyman I., Dean K. Outcomes of public concern in schizophrenia // British journal of psychiatry. 2007. Vol. 191, Suppl. 50. pp. S29-S36.

Kulhara P. Outcome of schizophrenia: some transcultural observations with particular reference to developing countries // European Archives of Psychiatry and Clinical Neuroscience. 1994. Vol. 244. № 5. pp. 227-235.

Abritalin E.Yu., Aleksandrovskii Yu.A., Anan'eva N.I. Psychiatry: national guide. 2nd ed., revis. and expan. Ed. by Yu.A. Aleksandrovskiу. M.: GEOTAR-Media, 2018. 896 p.

Analytical report of the Research Institute of Mental Health of the Russian Academy of Sciences «Epidemiology and economics of schizophrenia in the Russian Federation» (2022). Tomsk: Research Institute of Mental Health, 2022. 78 p.

IMS (RMBC) retail audit database for medicines in the Russian Federation // ims.com. 2026.

PubMed database // pubmed.ncbi.nlm.nih.gov. 2026.

Data of the Ministry of Health of the Republic of Belarus (2023) // minzdrav.gov.by. 2026.

Data of the Ministry of Health of the Russian Federation (2023) // minzdrav.gov.ru. 2026.

Data of the National Statistical Committee of the Republic of Belarus (Belstat, 2023) // belstat.gov.by. 2026.

Data of the Federal State Statistics Service (Rosstat, 2023) // rosstat.gov.ru. 2026.

WHO report «Mental Health Atlas 2020» on the state of mental health services in European countries. Geneva: WHO, 2020. 184 p.

Law of the Republic of Belarus dated 18.06.1993 No. 2435-XII «On health care» (as amended on 09.01.2023) // Supreme Council of the Republic of Belarus bulletin. 1993. № 27. Art. 327.

Constitution of the Republic of Belarus: adopted at the republican referendum on 24.11.1996 with amendments and additions. Minsk: National Center of Legal Information of the Republic of Belarus, 2023. 96 p.

Constitution of the Russian Federation: adopted by nationwide vote on 12.12.1993 with amendments introduced by the laws of the Russian Federation on amendments to the Constitution of the Russian Federation dated 30.12.2008 № 6-FKZ, dated 30.12.2008 № 7-FKZ. M.: Iuridicheskaia literatura, 2023. 64 p.

Liubov E.B. Cost analysis of the burden of schizophrenia in the Russian Federation: epidemiological and economic aspects // Social and clinical psychiatry. 2010. Vol. 20. № 3. pp. 5-12.

Liubov E.B., Iastrebov V.S., Shevchenko L.S. Economic burden of schizophrenia in Russia. M.: Moscow Research Institute of Psychiatry, 2009. 124 p.

International statistical classification of diseases and related health problems, 10th revision (ICD-10). Geneva: WHO, 1992.

Scientific electronic library eLibrary.ru // elibrary.ru. 2026.

Report of the Ministry of Health of the Republic of Belarus «State of mental health of the population of the Republic of Belarus» (2022). Minsk: Ministry of Health of the Republic of Belarus, 2022. 56 p.

Official website of the World Health Organization // who.int. 2026.

Federal Law dated 21.11.2011 № 323-FZ «On the fundamentals of health protection of citizens in the Russian Federation» // Collected Legislation of the Russian Federation. 2011. № 48. Art. 6724.

Shilova O.V. Economic aspects of medical care for patients with schizophrenia // Health care. 2018. № 1. pp. 33-40.

Shilova O.V. Economic aspects of medical care for patients with schizophrenia. Gomel: Gomel State Medical University, 2018. 92 p.

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